The AD-protective SNP allele reduces the proportion of CD33 encoding functional CD33 and thereby effectively inhibits CD33 to promote microglial activation [60, 61, 74C76]. INPP5D (SHIP1) The SH2-containing SHIP1 isoform
ROCK inhibitors
The AD-protective SNP allele reduces the proportion of CD33 encoding functional CD33 and thereby effectively inhibits CD33 to promote microglial activation [60, 61, 74C76]. INPP5D (SHIP1) The SH2-containing SHIP1 isoform